Current Aspects of the Neurosciences: Volume 3


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Abstract Full text PDF. Preview Abstract Objective:The purpose of this article was to determine the efficacy and tolerability of quetiapine compared with placebo or other interventions for psychosis in parkinsonism.


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Methods:Participants with a diagnosis of parkinsonism participated in randomized The authors conducted a historical cohort study involving Preview Abstract Objective:Self-monitoring is a crucial component of human empathy and necessary for the formation and repair of social relations. Several studies have brought to light possible neuronal substrates associated with self-monitoring, but the information that Preview Abstract Objective:Subtle and gradual changes occur in the brain years before cognitive impairment due to age-related neurodegenerative disorders. The authors examined the utility of hippocampal texture analysis and volumetric features extracted from brain Preview Abstract Objective:Depression is a highly prevalent neuropsychiatric sequela among individuals who have experienced traumatic brain injury TBI.

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Despite its high prevalence, there continues to be conflicting evidence surrounding the efficacy of medication for Preview Abstract Objective:Response inhibition has been frequently studied in obsessive-compulsive disorder OCD with mixed results. The inconsistent findings may stem in part from failure to consider the heterogeneity of the disorder. Methods:The authors examined The authors aimed to identify its occurrence in adolescents and confirm its existence in adults.

Given the association of the disorder with somatic Preview Abstract Objective:Previous studies have suggested that autoantibodies associated with systemic autoimmune disorders are more prevalent in patients with psychotic and affective disorders compared with healthy control subjects. However, most positive studies Preview Abstract Objective:The recent advent of individualized resting-state network mapping RSNM has revealed substantial interindividual variability in anatomical localization of brain networks identified by using resting-state functional MRI rsfMRI.

Results: Overall, 32 trials were included.

Jeff Lichtman (Harvard) Part 1: Connectomics: seeking neural circuit motifs

The use of a large mirror compared to a small mirror showed a higher effect on motor function. Movements executed unilaterally showed a higher effect on motor function than a bilateral execution. MT exercises including manipulation of objects showed a minor effect on motor function compared to movements excluding the manipulation of objects.


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  6. None of the subgroup differences reached statistical significance. Conclusions: The results of this analysis suggest that the effects on both motor function and impairment of the affected upper limb depend on the therapy protocol. They furthermore indicate that a large mirror, unilateral movement execution and exercises without objects may be parameters that enhance the effects of MT for improving motor function after stroke.

    Show more. Keywords: Stroke, paresis, rehabilitation, mirror therapy, meta-analysis.

    DOI: Citation: Restorative Neurology and Neuroscience , vol. Pre-press, no. Pre-press, pp. Abstract: Background: Excitatory brain stimulation, in the form of intermittent theta burst stimulation iTBS , combined with mirror visual feedback MVF , is hypothesized to promote neuroplasticity and motor performance. Objective: This study aimed to investigate the combined effects of iTBS with mirror training MT on the MVF-induced sensorimotor event-related desynchronization ERD and the non-dominant hand motor performance in healthy adults. For participants in Groups 1 and 3, … motor training was performed for 15 minutes for the right hand over four consecutive days, with MVF superimposing on their inactive left hand behind a mirror.

    Participants in Group 2 received the same right-hand motor training, but the mirror was covered without MVF. Motor performance was assessed at baseline and post-training. No significant between-group difference in motor outcomes was observed. Keywords: Theta burst stimulation, mirror visual feedback, event-related desynchronization, mirror neuron system. Abstract: Background: Repetitive transcranial magnetic stimulation rTMS is a promising treatment for chronic intractable neuropathic pain in patients with spinal cord injury SCI.

    However, the analgesia-enhancing effects of rTMS on conventional interventions e. Objective: To investigate the enhancement of analgesia and change of cortex activation by rTMS treatment on neuropathic pain following SCI. Methods: A double-blind, sham-controlled, clinical trial was performed. In addition, the numerical rating scale NRS was used to assess pain. Along with the time, the pain intensity gradually decreased in both the rTMS and sham groups. The real rTMS, compared with the sham, showed more pain relief from two weeks T3 to six weeks T5 , and the activations of the motor-related areas M1 and PMC were remarkably suppressed.

    Conclusions: The findings of this preliminary study with a small patient sample suggest that the analgesia-enhancing effects of high-frequency rTMS might be related with the amelioration of M1 and PMC hypersensitivity, shedding light upon the clinical treatment of SCI-related neuropathic pain.

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    Authors: Bakker, C. Massa, M. Daffertshofer, A. Pasman, J.


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    Stegeman, D. Abstract: Background: Within the first 72 hours after stroke, active finger extension is a strong predictor of long-term dexterity. Transcranial magnetic stimulation may add prognostic value to clinical assessment, which is especially relevant for patients unable to follow instructions. Objective: The current prospective cohort study aims at determining whether amplitude of motor evoked potentials of the extensor digitorum communis EDC can improve clinical prediction after stroke when added to clinical tests.

    For comparison, also the MEP amplitudes of biceps brachii and adductor digiti minimi muscles were recorded. Keywords: Transcranial magnetic stimulation TMS , upper extremity, prognosis.

    Journal of neuroscience impact factor 12222

    Authors: Gaston, Tyler E. Nair, Sangeeta Allendorfer, Jane B. Martin, Roy C. Abstract: Background: Memory deficits are very common in epilepsy, but no standard of care exists to effectively manage them.

    Current Aspects of the Neurosciences: Volume 3 Current Aspects of the Neurosciences: Volume 3
    Current Aspects of the Neurosciences: Volume 3 Current Aspects of the Neurosciences: Volume 3
    Current Aspects of the Neurosciences: Volume 3 Current Aspects of the Neurosciences: Volume 3
    Current Aspects of the Neurosciences: Volume 3 Current Aspects of the Neurosciences: Volume 3
    Current Aspects of the Neurosciences: Volume 3 Current Aspects of the Neurosciences: Volume 3

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